About Me
I was 6 years old when open heart surgery saved my brother’s life. It was the first of many times when I thought about becoming a doctor, so that I, too, could save someone’s life. For more than 40 years, I’ve had that opportunity. At Smilow Comprehensive Prostate Cancer Center, part of NYU Langone’s Perlmutter Cancer Center, I’ve treated more than 5,000 patients with prostate cancer. The majority of these men have been cured and their quality of life preserved after having their prostate gland removed through a procedure known as radical prostatectomy.
I came to NYU Langone in 1993 because I had a tremendous opportunity to build a world-class urology department here. Since then, our department has defined innovative care by improving outcomes for radical prostatectomy. For example, we now use a technique that spares the nerves, preserving function as much as possible. We also pioneered the use of MRI to diagnose and pinpoint the precise location of prostate cancer. More than 90 percent of patients who’ve needed surgery to remove the prostate at NYU Langone have reported long-term satisfaction with the outcomes.
We are at the forefront of prostate cancer research using image-guided diagnostic techniques, such as MRI, to help us determine the best treatment—whether it’s surveilling a slow-growing cancer, completely removing the prostate, or destroying one malignant area in an outpatient procedure that has virtually no treatment-related complications. I have had the pleasure of presenting these innovations at academic meetings throughout the United States and the world.
It’s the connection we make with patients and their families that humanizes medicine in this age of technology. For this reason, I take time to listen to my patients and guide them through treatment. Every step of the way we share the decision-making process for screening, detection, and treatment of prostate cancer.
Conditions and Treatments
Conditions
- benign prostatic hypertrophy
- cancer
- elevated prostate-specific antigen
- genitourinary neoplasm
- high grade prostatic intraepithelial neoplasia (hgpin)
- prostate cancer
Treatments
- excision of prostate
- focal ablation
- mri ultrasound fusion guided biopsy
Learn more about conditions we treat at NYU Langone:
Prostate CancerCredentials
Positions
- Professor, Department of Biochemistry and Molecular Pharmacology at NYU Grossman School of Medicine
- Professor, Department of Urology at NYU Grossman School of Medicine
- Martin Spatz Chair, Department of Urology
- Chief, Urology
Board Certifications
- American Board of Urology - Urology, 1987
Education and Training
- Residency, Johns Hopkins Hospital, 1985
- Residency, Johns Hopkins Hospital, 1981
- MD from Johns Hopkins University, 1979
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Edit profileInsurance Plans Accepted
This provider accepts the following insurance plans.
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Aetna
- Aetna HMO
- Aetna Indemnity
- Aetna International
- Aetna Open Access EPO
- Aetna Open Access HMO
- Aetna POS
- Aetna POS (American Express Employer)
- Aetna PPO
- Aetna Signature Administrators PPO
- Aetna Student Plan
- Allied
- Chesterfield Resources Inc
- Christian Brothers Services
- CoreSource
- Nippon Life of America-Aetna
- Nippon Life-Aetna
- Starmark
- WellNet
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Anthem Blue Cross Blue Shield
- Anthem BCBS CT PPO
- Anthem BCBS CT Pathway PPO
- BCBS Blue Access EPO Large Group
- BCBS Blue Access EPO Small Group
- BCBS Blue Access GEPO Small Group
- BCBS Blue Access PPO Large Group
- BCBS EPO
- BCBS EPO (BlackRock Employees)
- BCBS EPO (LICH Employees)
- BCBS EPO - Empire EPO (NYU Langone Employees)
- BCBS EPO - Empire EPO (Sunset Park/Family Health Center Employees)
- BCBS EPO - Empire NYU Care (NYU Langone Employees)
- BCBS EPO - Empire NYU Care (Sunset Park/Family Health Center Employees)
- BCBS Federal Program
- BCBS Florida Blue Care HMO
- BCBS Florida Blue Options PPO
- BCBS Florida Blue Select
- BCBS Florida MyBlue HMO
- BCBS Florida Simply Blue
- BCBS Florida Traditional PPC
- BCBS HMO
- BCBS Indemnity
- BCBS Local 32BJ Employees
- BCBS POS
- BCBS PPO
- BCBS PPO (BlackRock Employees)
- BCBS PPO (LICH Employees)
- BCBS PPO - Empire PPO (Sunset Park/Family Health Center Employees)
- BCBS PPO/EPO Small Group
- New York Hotel Trades
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Cigna
- Apwu Health Plan
- Cigna - Humana
- Cigna Great West PPO
- Cigna HMO
- Cigna Indemnity
- Cigna Managed Care/POS
- Cigna NALC
- Cigna Open Access
- Cigna Open Access PPO
- Cigna Oscar
- Cigna PPO
- Cigna Premier Plus
- Great West HMO
- Kaiser Permanente
- MVP-Cigna Network
- Wellfleet-NYU Student
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First Health
- First Health PPO
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Magnacare
- Magnacare PPO
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Multiplan
- AXA Assistance USA
- Administrative Concepts
- Beech Street PPO
- Diversified Administration Corporation
- Fiserv Health
- GEHA
- Global Excel
- Global Health
- Guardian Life Insurance Co Of America
- Health Net Of California
- Health Republic Of NJ
- Insurance Design Administrators
- Kaiser Foundation
- Kaiser Permanente
- Meritain Health
- Multiplan PPO
- Multiplan-Capital Dist Phys Health
- Mutual Of Omaha
- Nippon Life Ins Co
- PHCS
- Professional Benefit Admin
- Qualcare Inc
- Screen Actors Guild
- Teamsters Allied Benefits
- US Life Insurance Company
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Oxford
- Oxford Health Plans Freedom
- Oxford Health Plans Liberty
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POMCO Insurance Company
- POMCO Insurance Company
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Qualcare Inc.
- Qualcare Direct
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Sedgwick WTC
- World Trade Center - Sedgwick
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United Healthcare
- Bind Benefits inc
- UMR
- United Healthcare (NY University Care Plan)
- United Healthcare All Savers
- United Healthcare Choice
- United Healthcare Choice (AMEX employees)
- United Healthcare Choice (Blackrock employees)
- United Healthcare Choice (CBS employees)
- United Healthcare Choice (Simon
- United Healthcare EPO
- United Healthcare EPO (NYU Langone Health Employees)
- United Healthcare Golden Rule Insurance
- United Healthcare HMO
- United Healthcare Healthscope
- United Healthcare Indemnity
- United Healthcare Indemnity (NYU Langone Health Employees)
- United Healthcare Navigate
- United Healthcare Nexus
- United Healthcare Nexus (Amex Employees)
- United Healthcare POS
- United Healthcare PPO
- United Healthcare Plus (NYU Langone Health Employees)
- United Healthcare Student Resources
- United Healthcare Student Resources (NYU)
- United Healthcare Value, Advantage and HDHP (New York University employees)
- UnitedHealthcare Choice (NY Power Authority Employees)
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VA Community Care Network
- VA CCN Optum
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WTC Health Program
- NY Fire Department - WTC
- WTC Health Program
Herbert Lepor, MD does not accept insurance.
Locations and Appointments
NYU Langone Urology Associates
222 East 41st Street, 12th Floor, New York, NY 10017
“We have worked to improve the technique for removing the prostate, preserving as many nerves as possible, leading to preservation of sexual function.”
Herbert Lepor, MD Urologic Oncologist
Research My Research
Interests
neuropharmacology and physiology of the prostate
Research Summary
We characterize the neuropharmacology and neurophysiology of the prostate. Thus far, we have characterized the alpha1, alpha2, muscarinic cholinergic, DHP, and endothelin receptors in the prostate using radioligand receptor-binding studies. Additionally, we determined the cellular localization and physiological role of these receptors using autoradiography, isometric tension studies, and in vivo studies. Recently, we characterized and localized the alpha1 adrenoceptor subtypes in the human prostate. The clinical relevance of these investigations relates to the management of benign prostatic hyperplasia (BPH), a very common disease that causes bladder dysfunction and lower urinary tract symptoms in the aging male population. Bladder outlet obstructions secondary to BPH appear to be an important factor in the pathophysiology of the disease process. Alpha1 antagonists are routinely used to treat BPH. The tension of prostate smooth muscle is mediated by the alpha1 endothelin receptors and nitric oxide. In future investigations, we will study the role of endothelin antagonists and nitric oxide agonists.
Academic Contact
Academic office
222 East 41st Street
11th and 12th Floors
New York, NY 10017
Phone
Research Interests Timeline
Clinical Trials and Research Studies
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Prospective Database of Clinical Outcomes Following Cryotherapy for ablation of clinically localized prostate cancer
Publications
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Lepor, Herbert; Rapoport, Eli; Tafa, Majlinda; Gogaj, Rozalba; Wysock, James S
Urology. 2024 Oct 22;
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Sawhney, Vyom; Huang, Richard; Huang, William C; Lepor, Herbert; Taneja, Samir S; Wysock, James
Urology. 2024 Sep 03;
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Sawhney, Vyom; Huang, Richard; Huang, William C; Lepor, Herbert; Taneja, Samir S; Wysock, James
Urology. 2024 Jul 14;