NYU Langone Provider

Leopoldo N. Segal, MD

NYU Langone Provider
  • Specialties: Critical Care, Pulmonary Medicine
  • Treats: Adults
  • Language: English
  • Phone: 212-263-7951
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Conditions and Treatments

  • chronic bronchitis
  • chronic obstructive pulmonary disease
  • emphysema
  • lung mass
  • lung metastasis
  • mediastinal lymphadenopathy
  • small mass of the lung
  • lung cancer screening
  • lung function test

Education and Training
  • Fellowship, NYU Medical Center, Pulmonary/Crit. Care, 2010
  • Residency, Morristown Memorial Hospital, 2007
  • MD from University Of La Plata, 1998

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This provider accepts the following insurance plans.

  • Anthem Blue Cross Blue Shield
    • Anthem BCBS CT PPO
    • Anthem BCBS CT Pathway PPO
    • BCBS Blue Access EPO Large Group
    • BCBS Blue Access EPO Small Group
    • BCBS Blue Access GEPO Small Group
    • BCBS Blue Access PPO Large Group
    • BCBS EPO
    • BCBS EPO (BlackRock Employees)
    • BCBS EPO (LICH Employees)
    • BCBS EPO - Empire EPO (NYU Langone Employees)
    • BCBS EPO - Empire EPO (Sunset Park/Family Health Center Employees)
    • BCBS EPO - Empire NYU Care (NYU Langone Employees)
    • BCBS EPO - Empire NYU Care (Sunset Park/Family Health Center Employees)
    • BCBS Federal Program
    • BCBS Florida Blue Care HMO
    • BCBS Florida Blue Medicare PPO
    • BCBS Florida Blue Options PPO
    • BCBS Florida Blue Select
    • BCBS Florida MyBlue HMO
    • BCBS Florida Simply Blue
    • BCBS Florida Traditional PPC
    • BCBS HMO
    • BCBS Indemnity
    • BCBS Local 32BJ Employees
    • BCBS Mediblue Medicare HMO
    • BCBS Mediblue Medicare PPO
    • BCBS Mediblue Select HMO/Extra HMO
    • BCBS POS
    • BCBS PPO
    • BCBS PPO (BlackRock Employees)
    • BCBS PPO (LICH Employees)
    • BCBS PPO - Empire PPO (Sunset Park/Family Health Center Employees)
    • BCBS PPO/EPO Small Group
    • New York Hotel Trades
  • Cigna
    • Apwu Health Plan
    • Cigna - Humana
    • Cigna Great West PPO
    • Cigna HMO
    • Cigna Indemnity
    • Cigna Managed Care/POS
    • Cigna Medicare Advantage
    • Cigna NALC
    • Cigna Open Access
    • Cigna Open Access PPO
    • Cigna Oscar
    • Cigna PPO
    • Cigna Premier Plus
    • Great West HMO
    • Kaiser Permanente
    • MVP-Cigna Network
    • Wellfleet-NYU Student
  • Connecticare
    • Connecticare Bridge
    • Connecticare Commercial
  • Elderplan
    • Elderplan
    • Elderplan FIDA
    • Elderplan Medicare Advantage Plan
  • Emblem
    • Emblem Select Care Bronze Small Group
    • Emblem Select Care EPO
    • Emblem Select Care Gold Small Group
    • Emblem Select Care HMO
    • Emblem Select Care PPO
    • Emblem Select Care Platinum Small Group
    • Emblem Select Care Silver Small Group
  • GHI
    • American Plan Administrators
    • GHI CBP (City of New York Employees)
    • GHI Emblem Health EPO
    • GHI Emblem Health PPO
    • GHI HMO
    • GHI HMO Medicare
    • GHI Medicare PPO
    • GHI Medicare Supplement
    • GHI Network Access - Benefit Services of PA
    • GHI Network Access - Humana
    • GHI Network Access - Total Plan Concepts
    • IUOE Local 14-14B
    • Wlny-TV Inc.
  • HIP
    • HIP Access I
    • HIP Access II
    • HIP Bridge
    • HIP Child Health Plus
    • HIP EPO
    • HIP HMO
    • HIP Medicare Supplement
    • HIP POS
    • HIP PPO
    • HIP Prime Basic Exchange
    • HIP Prime Bronze
    • HIP Prime Bronze Exchange
    • HIP Prime Catastrophic Exchange
    • HIP Prime Gold
    • HIP Prime Gold Exchange
    • HIP Prime Platinum
    • HIP Prime Platinum Exchange
    • HIP Prime Silver
    • HIP Prime Silver Exchange
    • HIP VIP Medicare Bold
    • HIP VIP Medicare Prime
    • Vytra HMO
  • Hotel Trades Council
    • Hotel Trades Council
  • Humana
    • Humana Medicare Advantage
  • Local 1199
    • Local 1199 - NYU Hospital Member Choice
    • Local 1199 PPO
  • Magnacare
    • Magnacare PPO
  • Medicare
    • Medicare Part A and B
    • Medicare Part B
  • Multiplan
    • AXA Assistance USA
    • Administrative Concepts
    • Beech Street PPO
    • Diversified Administration Corporation
    • Fiserv Health
    • GEHA
    • Global Excel
    • Global Health
    • Guardian Life Insurance Co Of America
    • Health Net Of California
    • Health Republic Of NJ
    • Insurance Design Administrators
    • Kaiser Foundation
    • Kaiser Permanente
    • Meritain Health
    • Multiplan PPO
    • Multiplan-Capital Dist Phys Health
    • Mutual Of Omaha
    • Nippon Life Ins Co
    • PHCS
    • Professional Benefit Admin
    • Qualcare Inc
    • Screen Actors Guild
    • Teamsters Allied Benefits
    • US Life Insurance Company
  • NYSHIP - The Empire Plan
    • NYS Health Insurance Plan - The Empire Plan, Excelsior Plan, NY Student Employee Health Plan
  • Oxford
    • Oxford Health Plans Freedom
    • Oxford Health Plans Liberty
  • POMCO Insurance Company
    • POMCO Insurance Company
  • Qualcare Inc.
    • Qualcare Direct
  • Railroad Medicare
    • Palmetto GBA Railroad Medicare
  • Sedgwick WTC
    • World Trade Center - Sedgwick
  • Tricare
    • TriWest
    • Tricare
    • US Family Health Plan
  • United Healthcare
    • AARP Medicare Complete
    • Bind Benefits inc
    • Oxford Health Plans Medicare Advantage
    • UMR
    • Unite Healthcare (NY University Care Plan)
    • United Healthcare AARP
    • United Healthcare All Savers
    • United Healthcare Choice
    • United Healthcare Choice (AMEX employees)
    • United Healthcare Choice (Blackrock employees)
    • United Healthcare Choice (CBS employees)
    • United Healthcare Choice (Simon
    • United Healthcare EPO
    • United Healthcare EPO (NYU Langone Health Employees)
    • United Healthcare Golden Rule Insurance
    • United Healthcare HMO
    • United Healthcare Healthscope
    • United Healthcare Indemnity
    • United Healthcare Indemnity (NYU Langone Health Employees)
    • United Healthcare Medicare
    • United Healthcare Navigate
    • United Healthcare Nexus
    • United Healthcare Nexus (Amex Employees)
    • United Healthcare POS
    • United Healthcare PPO
    • United Healthcare Plus (NYU Langone Health Employees)
    • United Healthcare Student Resources
    • United Healthcare Student Resources (NYU)
    • United Healthcare Value, Advantage and HDHP (New York University employees)
    • UnitedHealthcare Choice (NY Power Authority Employees)
  • VA Community Care Network
    • VA CCN Optum
  • VNS Choice Advantage
    • VNS Medicare Advantage
    • VNS NY Choice Select Health
  • Village Care
    • VillageCare
  • WTC Health Program
    • NY Fire Department - WTC
    • WTC Health Program
View All Accepted Plans This list of insurances changes regularly, and insurance plans listed may not be accepted at all office locations for this provider. Before your appointment, please confirm with your insurance company that this provider accepts your insurance.

Leopoldo N. Segal, MD does not accept insurance.

Locations and Appointments

NYU Langone Pulmonary & Critical Care Associates

222 East 41st Street, 21st Floor, New York, NY 10017

Research Summary

My interest is to understand the mechanism by which inflammation occurs in Chronic Obstructive Pulmonary Disease (COPD) leading to lung parenchyma destruction and airway remodeling. In the Andre Cournand Pulmonary Physiology Laboratory we can study the distal airway function in patients with early COPD. My focus is on understanding the mechanisms that occur early in the development of this disease where therapeutic approaches might be more efficacious. Although the lung is classically though to be sterile, in COPD increased bacterial colonization leads to airway inflammation and accelerated airway obstruction. The reliance on culture data and contamination by oral flora has limited the ability to understand the effect of airway bacterial load on airway inflammation in early COPD. The study of the microbiome using ribosomal DNA sequence has now opened an opportunity to directly characterize resident microbial flora without the need for bacterial culture. As a pulmonologist, I have sampled the lower airway by bronchoscopy and have exploited recent development next generation rDNA sequence to define complex microbial communities of commensal lung bacteria that we have called a pneumotype. We have found significant bacterial DNA in subjects with early COPD and we evaluate how this pneumotype affects the innate and humoral immunity in the lung of patients with early COPD. By studying how the lung microbiome alters the lung immune response I hope to understand the physiological changes that occurs early in this disease and we may discover new therapeutic targets for patients with obstructive airways disease.

Academic Contact

Lab Website

These focus areas and their associated publications are derived from PubMed and the MeSH term library. *
represents one publication
*Due to PubMed processing times, the most recent publications may not be reflected in the timeline.

  • Microbial and host biomarkers for endotyping critically ill patients

    Learn More
  • Microbial and human biomarkers of thoracic disease after lung transplantation

    Learn More
  • Registry of COVID-19 Survivors: Assessment of ICU and Non-ICU Survivors: A Creation of a COVID Survivorship Database

    Learn More
View All Research Studies (3)

  • Zinter, Matt S; Dvorak, Christopher C; Mayday, Madeline Y; Reyes, Gustavo; Simon, Miriam R; Pearce, Emma M; Kim, Hanna; Shaw, Peter J; Rowan, Courtney M; Auletta, Jeffrey J; Martin, Paul L; Godder, Kamar; Duncan, Christine N; Lalefar, Nahal R; Kreml, Erin M; Hume, Janet R; Abdel-Azim, Hisham; Hurley, Caitlin; Cuvelier, Geoffrey D E; Keating, Amy K; Qayed, Muna; Killinger, James S; Fitzgerald, Julie C; Hanna, Rabi; Mahadeo, Kris M; Quigg, Troy C; Satwani, Prakash; Castillo, Paul; Gertz, Shira J; Moore, Theodore B; Hanisch, Benjamin; Abdel-Mageed, Aly; Phelan, Rachel; Davis, Dereck B; Hudspeth, Michelle P; Yanik, Greg A; Pulsipher, Michael A; Sulaiman, Imran; Segal, Leopoldo N; Versluys, Birgitta A; Lindemans, Caroline A; Boelens, Jaap J; DeRisi, Joseph L; ,

    Nature medicine. 2024 May 23;

  • Nyawo, Georgina; Naidoo, Charissa; Wu, Benjamin G; Kwok, Benjamin; Clemente, Jose C; Li, Yonghua; Minnies, Stephanie; Reeve, Byron; Moodley, Suventha; John, Thadathilankal-Jess; Karamchand, Sumanth; Singh, Shivani; Pecararo, Alfonso; Doubell, Anton; Kyriakakis, Charles; Warren, Robin; Segal, Leopoldo N; Theron, Grant

    medRxiv : the preprint server for health sciences. 2024 Apr 27;

  • Budden, Kurtis F; Shukla, Shakti D; Bowerman, Kate L; Vaughan, Annalicia; Gellatly, Shaan L; Wood, David L A; Lachner, Nancy; Idrees, Sobia; Rehman, Saima Firdous; Faiz, Alen; Patel, Vyoma K; Donovan, Chantal; Alemao, Charlotte A; Shen, Sj; Amorim, Nadia; Majumder, Rajib; Vanka, Kanth S; Mason, Jazz; Haw, Tatt Jhong; Tillet, Bree; Fricker, Michael; Keely, Simon; Hansbro, Nicole; Belz, Gabrielle T; Horvat, Jay; Ashhurst, Thomas; van Vreden, Caryn; McGuire, Helen; Fazekas de St Groth, Barbara; King, Nicholas J C; Crossett, Ben; Cordwell, Stuart J; Bonaguro, Lorenzo; Schultze, Joachim L; Hamilton-Williams, Emma E; Mann, Elizabeth; Forster, Samuel C; Cooper, Matthew A; Segal, Leopoldo N; Chotirmall, Sanjay H; Collins, Peter; Bowman, Rayleen; Fong, Kwun M; Yang, Ian A; Wark, Peter A B; Dennis, Paul G; Hugenholtz, Philip; Hansbro, Philip M

    Gut. 2024 Apr 05; 73(5):751-769

Read All Publications (169)

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