Chemotherapy for Endometrial Cancer

NYU Langone gynecologic oncologists may prescribe chemotherapyā€”drugs that destroy cancer cellsā€”for women with endometrial cancer that has spread throughout the body after surgery. In some instances, chemotherapy may be used in combination with radiation therapy, an approach called chemoradiation.

Chemotherapy drugs are given through a vein with an intravenous (IV) infusion. Your doctor determines the number of treatments needed based on the stage of the cancer.

NYU Langone specialists conduct clinical trials to evaluate the effectiveness of new chemotherapy drugs and new combinations of chemotherapy drugs for women with endometrial cancer. Your doctor can tell you if you are eligible to participate in one of these trials.

Managing Side Effects

Our doctors are careful to prescribe the chemotherapy dose that is most effective and causes the fewest side effects. Still, you may experience nausea, vomiting, loss of appetite, mouth sores, hair loss, or neuropathyā€”nerve damage that can cause numbness, tingling, pain, and weakness. Your doctor can prescribe medication to alleviate these side effects and suggest integrative therapies that may provide additional assistance.

Some chemotherapy drugs trigger menopause in women who still have their ovaries. If you want to have children after treatment for endometrial cancer, your doctor can discuss fertility-preserving options with you and refer you to the reproductive medicine specialists at NYU Langoneā€™s Fertility Center and NYU Langone Reproductive Specialists of New York.

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